Hydrophilic, pH-sensitive fluorescent dye containing one carboxylic acid group and pKa in the physiological pH range (pKa = 7.1).
Applications
pH-Sensitive, fluorescent probe.
Cell-based imaging applications of e.g. receptor translocations, plasma membrane associated receptor activation or GPCR-ligand interactions via constitutive endocytosis.
Advantages
Perfectly suited for excitation with the 594, 635 and 650-nm diode lasers.